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Evidence found and GRADE certainty

25 questions · 25 findings · 5 reviews

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No studies found 0 · 0%GRADE not reported 3 · 12%Very low 5 · 20%Low 10 · 40%Moderate 5 · 20%High 2 · 8%

Fluoroquinolone substitution for isoniazid in a standard six month regimen vs standard regimen

Death from any cause · Patients with presumed drug‐sensitive TB

Fluoroquinolone substitution for isoniazid in a standard six month… showed no clear difference in death from any cause compared with standard regimen (low certainty).

1 finding from 1 review

Fluoroquinolone substitution for isoniazid in a standard six month regimen vs standard regimen

TB‐related death · Patients with presumed drug‐sensitive TB

Fluoroquinolone substitution for isoniazid in a standard six month… showed no clear difference in TB‐related death compared with standard regimen (low certainty).

1 finding from 1 review

Fluoroquinolone substitution for isoniazid in a standard six month regimen vs standard regimen

Sputum culture conversion at 8 weeks · Patients with presumed drug‐sensitive TB

Fluoroquinolone substitution for isoniazid in a standard six month… showed no clear difference in sputum culture conversion at 8 weeks compared with standard regimen (low certainty).

1 finding from 1 review

Fluoroquinolone substitution for isoniazid in a standard six month regimen vs standard regimen

Serious adverse events · Patients with presumed drug‐sensitive TB

Fluoroquinolone substitution for isoniazid in a standard six month… showed no clear difference in serious adverse events compared with standard regimen (low certainty).

1 finding from 1 review