What do systematic reviews say?

Intravenous immunoglobulin with or without standard care vs placebo or usual care

It is very uncertain whether intravenous immunoglobulin with or without standard care changes significant disability assessed using Liverpool Outcome Score RR… compared with standard care alone or placebo (very low certainty).

• Intravenous immunoglobulin for the treatment of childhood encephalitis 2017 · Cochrane Headline outcomes only
  RR 0.75 [0.22, 2.6]
  1 study · 22 participants
  Very low

Intravenous immunoglobulin with or without standard care vs placebo or usual care

It is very uncertain whether intravenous immunoglobulin with or without standard care changes ≥ 1 serious adverse event RR (M‐H, random‐effects analysis, 95% CI) compared with standard care alone or placebo (very low certainty).

• Intravenous immunoglobulin for the treatment of childhood encephalitis 2017 · Cochrane Headline outcomes only
  RR 1 [0.07, 14.05]
  1 study · 22 participants
  Very low

Intravenous immunoglobulin with or without standard care vs placebo or usual care

• Intravenous immunoglobulin for the treatment of childhood encephalitis 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 116 participants
  Very low