Intravenous may leads to lower relapse at 6 months compared with oral cyclophosphamide (low certainty).
Intravenous may leads to lower continuing frequently‐relapsing or steroid‐dependent SSNS at 6 months compared with oral cyclophosphamide (low certainty).
Intravenous showed no clear difference in relapse at end of study compared with oral cyclophosphamide (low certainty).
The review found no eligible studies for this question.
Intravenous showed no clear difference in adverse events: leucopenia compared with oral cyclophosphamide (low certainty).
Intravenous showed no clear difference in adverse events: hair loss compared with oral cyclophosphamide (low certainty).
Intravenous may leads to lower adverse events: all infections compared with oral cyclophosphamide (low certainty).
It is very uncertain whether intravenous changes adverse events: nausea and vomiting compared with oral cyclophosphamide (very low certainty).
Intravenous immunoglobulin showed no clear difference in death compared with placebo (low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
Intravenous immunoglobulin may leads to higher response at 3 months compared with placebo (low certainty).
Intravenous immunoglobulin showed no clear difference in relapse at 3 months compared with placebo (low certainty).
Intravenous immunoglobulin may leads to higher adverse events compared with placebo (low certainty).
The review found no eligible studies for this question.
It is very uncertain whether intravenous ± oral steroids changes adverse events: thromboses compared with oral steroids alone (very low certainty).
It is very uncertain whether intravenous ± oral steroids changes adverse events: gastrointestinal bleeding compared with oral steroids alone (very low certainty).
It is very uncertain whether intravenous ± oral steroids changes complete remission Time frame: 2 to 28 months compared with oral steroids alone (very low certainty).
The review found no eligible studies for this question.
It is very uncertain whether intravenous ± oral steroids changes relapse during compared with oral steroids alone (very low certainty).