Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,183 questions · 2,385 findings · 241 reviews

No studies found 558 · 23.4%GRADE not reported 158 · 6.6%Very low 704 · 29.5%Low 618 · 25.9%Moderate 276 · 11.6%High 71 · 3%

Active stimulation + other intervention vs other intervention alone

Pain intensity VAS (0 to 100; 0 = no pain, 100 = worst pain) · adults with chronic pain
3 findings from 1 review

Active stimulation + other intervention vs other intervention alone

Participant‐reported pain relief of 50% or greater · adults with chronic pain

It is very uncertain whether active stimulation + other intervention changes pain intensity. Proportion with ≥ 50% pain relief. compared with other intervention alone (very low certainty).

1 finding from 1 review

Active stimulation + other intervention vs other intervention alone

Adverse event: lead failure/ displacement · adults with chronic pain

The review found no eligible studies for this question.

3 findings from 1 review

Active stimulation + other intervention vs other intervention alone

Pain intensity (number of people with ≥ 50% improvement) · adults with chronic pain

Active stimulation + other intervention may leads to higher pain intensity. Proportion with ≥50% pain relief. compared with other intervention alone (low certainty).

2 findings from 1 review

Single‐component hydration intervention vs control

Incidence of delirium · people at risk of delirium in institutional long‐term care

It is very uncertain whether single‐component hydration intervention changes incidence of delirium NEECHAM Confusion Scale compared with control (very low certainty).

1 finding from 1 review