Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,183 questions · 2,385 findings · 241 reviews

No studies found 558 · 23.4%GRADE not reported 158 · 6.6%Very low 704 · 29.5%Low 618 · 25.9%Moderate 276 · 11.6%High 71 · 3%

Combined interventions vs no intervention

Re‐employment Measured as percentage or number of participants who obtained paid employment · Unemployed job seekers

Combined interventions probably leads to higher re‐employment Measured as percentage or number of participants who… compared with no intervention (moderate certainty).

2 findings from 1 review

Combined interventions vs usual care

Proportion of participants returning to work in the short term (up to 6 months) · patients with coronary heart disease

Combined interventions may leads to higher proportion of participants returning to work in the short term (up… compared with usual care (low certainty).

1 finding from 1 review

Combined interventions vs usual care

Proportion of participants returning to work in the medium term (6 months ‐ 1 year) · patients with coronary heart disease

Combined interventions showed no clear difference in proportion of participants returning to work in the medium term (6… compared with usual care (low certainty).

1 finding from 1 review

Combined interventions vs usual care

Return to work · patients with coronary heart disease

It is very uncertain whether combined interventions changes proportion of participants at work in the long term (> 1 to < 5 years) compared with usual care (very low certainty).

2 findings from 1 review

Combined interventions vs usual care

Proportion of participants at work in the extended long term (≥ 5 years) · patients with coronary heart disease

It is very uncertain whether combined interventions changes proportion of participants at work in the extended long term (≥ 5… compared with usual care (very low certainty).

1 finding from 1 review

Exercise vs usual care

Aerobic exercise tolerance (all cancers: 8 to 12 weeks of
3 findings from 1 review

Intervention diet vs usual on‐treatment diet

Diarrhoea (grade 2+) · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer

Summary of findings: Diet interventions showed no clear difference in diarrhoea (grade 2+) compared with usual on‐treatment diet (low certainty).

1 finding from 1 review

Intervention diet vs usual on‐treatment diet

QoL · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer

Summary of findings: Diet interventions showed no clear difference in QOL scores (IBDQ) (higher scores better) compared with usual on‐treatment diet (low certainty).

3 findings from 1 review

Intervention diet vs usual on‐treatment diet

Diarrhoea (grade 1+) · People undergoing pelvic radiotherapy for urological, gynaecological or colorectal cancer

Summary of findings: Diet interventions showed no clear difference in diarrhoea (grade 1+) compared with usual on‐treatment diet (low certainty).

1 finding from 1 review