Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

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No studies found 1 · 20%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 4 · 80%High 0 · 0%

Intermittent LTRA vs placebo

Serious adverse events · episodic viral wheeze in children

The review found no eligible studies for this question.

1 finding from 1 review

Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intermittent LTRA vs placebo

Number of participants experiencing one or more episode requiring treatment with oral steroids · episodic viral wheeze in children

Intermittent LTRA showed no clear difference in number of participants experiencing one or more episode requiring… compared with placebo (moderate certainty).

1 finding from 1 review

Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children 2015 · Cochrane Headline outcomes only
RR 0.85 [0.64, 1.14]
2 studies · 343 participants
Moderate

Intermittent LTRA vs placebo

Number of participants experiencing one or more episodes requiring ED visit · episodic viral wheeze in children

Intermittent LTRA showed no clear difference in number of participants experiencing one or more episodes requiring… compared with placebo (moderate certainty).

1 finding from 1 review

Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children 2015 · Cochrane Headline outcomes only
OR 1 [0.49, 2.02]
1 study · 141 participants
Moderate

Intermittent LTRA vs placebo

Number of participants experiencing one or more episodes requiring hospital admission · episodic viral wheeze in children

Intermittent LTRA showed no clear difference in number of participants experiencing one or more episodes requiring… compared with placebo (moderate certainty).

1 finding from 1 review

Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children 2015 · Cochrane Headline outcomes only
OR 0.73 [0.2, 2.73]
1 study · 141 participants
Moderate

Intermittent LTRA vs placebo

Total number of withdrawals · episodic viral wheeze in children

Intermittent LTRA showed no clear difference in withdrawals ‐ Total number of withdrawals compared with placebo (moderate certainty).

1 finding from 1 review

Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children 2015 · Cochrane Headline outcomes only
OR 1.03 [0.79, 1.35]
2 studies · 1402 participants
Moderate