Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 6 · 100%Moderate 0 · 0%High 0 · 0%

Interleukin‐2 RA vs polyclonal antibody induction

Mortality Mortality at latest · heart transplant recipients

Interleukin‐2 RA showed no clear difference in mortality Mortality at latest compared with polyclonal antibody induction (low certainty).

1 finding from 1 review

Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
RR 1.1 [0.65, 1.88]
4 studies · 185 participants
Low

Interleukin‐2 RA vs polyclonal antibody induction

Acute rejection Acute rejection grade 3A or more verified by biopsy · heart transplant recipients

Interleukin‐2 RA may leads to higher acute rejection Acute rejection grade 3A or more verified by biopsy compared with polyclonal antibody induction (low certainty).

1 finding from 1 review

Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
RR 2.43 [1.01, 5.86]
4 studies · 185 participants
Low

Interleukin‐2 RA vs polyclonal antibody induction

Infection Number of participants diagnosed with infection · heart transplant recipients

Interleukin‐2 RA showed no clear difference in infection Number of participants diagnosed with infection compared with polyclonal antibody induction (low certainty).

1 finding from 1 review

Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
RR 0.85 [0.71, 1.03]
3 studies · 155 participants
Low

Interleukin‐2 RA vs polyclonal antibody induction

CMV infection · heart transplant recipients

Interleukin‐2 RA showed no clear difference in cytomegalovirus infection Number of participants diagnosed with CMV… compared with polyclonal antibody induction (low certainty).

1 finding from 1 review

Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
RR 0.97 [0.53, 1.75]
4 studies · 185 participants
Low

Interleukin‐2 RA vs polyclonal antibody induction

Post‐transplantation lymphoproliferative disorder Number of participants diagnosed with PTLD · heart transplant recipients

1 finding from 1 review

Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 185 participants
Low

Interleukin‐2 RA vs polyclonal antibody induction

Cancer · heart transplant recipients

Interleukin‐2 RA showed no clear difference in cancer Number of participants diagnosed with cancer compared with polyclonal antibody induction (low certainty).

1 finding from 1 review

Immunosuppressive T‐cell antibody induction for heart transplant recipients 2013 · Cochrane Headline outcomes only
RR 9 [0.52, 156.91]
4 studies · 185 participants
Low