What do systematic reviews say?

INTEGRATED MODELS OF CARE vs usual care

Integrated models of care showed no clear difference in leaving the study early: Lost to treatment compared with standard care (low certainty).

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  RR 1.09 [0.82, 1.45]
  3 studies · 603 participants
  Low

INTEGRATED MODELS OF CARE vs usual care

Integrated models of care showed no clear difference in adverse event: Death compared with standard care (low certainty).

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  RR 1.18 [0.39, 3.57]
  2 studies · 421 participants
  Low

INTEGRATED MODELS OF CARE vs usual care

Integrated models of care showed no clear difference in substance use: any change ‐ Alcohol use (not in remission) compared with standard care (low certainty).

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  RR 1.15 [0.84, 1.56]
  1 study · 143 participants
  Low

INTEGRATED MODELS OF CARE vs usual care

Integrated models of care showed no clear difference in substance use: any change ‐ Drug use (not in remission) compared with standard care (low certainty).

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  RR 0.89 [0.63, 1.25]
  1 study · 85 participants
  Low

INTEGRATED MODELS OF CARE vs usual care

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 3 participants
  GRADE not reported

INTEGRATED MODELS OF CARE vs usual care

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 171 participants
  Low

INTEGRATED MODELS OF CARE vs usual care

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 372 participants
  Moderate

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

The review found no eligible studies for this question.

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

The review found no eligible studies for this question.

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

The review found no eligible studies for this question.

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 50 participants
  Very low

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

The review found no eligible studies for this question.

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

It is very uncertain whether non‐integrated models of care ‐ Assertive community treatment… changes leaving the study early: Lost to treatment compared with standard care (very low certainty).

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  RR 1.21 [0.73, 1.99]
  3 studies · 134 participants
  Very low

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

The review found no eligible studies for this question.

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found