Serious adverse events (n/N)
Summary of findings: insulin degludec showed no clear difference in serious adverse events (n/N) compared with insulin detemir (low certainty).
1 finding from 1 review
HbA1c (%)
1 finding from 1 review
All‐cause mortality
It is very uncertain whether summary of findings: insulin degludec changes all‐cause mortality compared with insulin glargine (very low certainty).
1 finding from 1 review
Health related quality of life the Uniscale and the Symptom Distress Scale (SDS); Better indicated by lower values
1 finding from 1 review
Severe hypoglycaemia
Summary of findings: insulin degludec showed no clear difference in severe hypoglycaemia (n/N) Definition: hypoglycaemia requiring third… compared with insulin glargine (low certainty).
1 finding from 1 review
Non‐fatal myocardial infarction/stroke Definition: myocardial infarction/cerebral ischaemia
1 finding from 1 review
Severe nocturnal hypoglycaemia (n/N) Definition: severe hypoglycaemia occurring from 22:00 to 06:59 h
Summary of findings: insulin degludec showed no clear difference in severe nocturnal hypoglycaemia (n/N) Definition: severe… compared with insulin glargine (low certainty).
1 finding from 1 review
Serious adverse events (n/N)
Summary of findings: insulin degludec showed no clear difference in serious adverse events (n/N) compared with insulin glargine (low certainty).
1 finding from 1 review
HbA1c (%)
1 finding from 1 review
Health‐related quality of life Scales: Well‐Being Enquiry for Diabetics; General Well‐being; Diabetes Quality of Life for Youth and Parents' Diabetes Quality of Life
1 finding from 1 review
Macrosomia · pregnant women with pre‐existing diabetes
1 finding from 1 review
Perinatal mortality · pregnant women with pre‐existing diabetes
1 finding from 1 review
Pre‐eclampsia · pregnant women with pre‐existing diabetes
1 finding from 1 review
Caesarean section · pregnant women with pre‐existing diabetes
1 finding from 1 review
Fetal anomaly (major) · pregnant women with pre‐existing diabetes
It is very uncertain whether insulin Detemir + prandial insulin Aspart changes fetal anomaly (major) compared with NPH insulin + prandial insulin Aspart (Different insulin types… (very low certainty).
1 finding from 1 review
Birth trauma including shoulder dystocia, nerve palsy, or fracture · pregnant women with pre‐existing diabetes
1 finding from 1 review
Composite outcome measure of neonatal morbidity · pregnant women with pre‐existing diabetes
1 finding from 1 review
Transplant or graft survival · pre‐existing and new‐onset diabetes in kidney transplant recipients
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Delayed graft function · pre‐existing and new‐onset diabetes in kidney transplant recipients
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
HbA1c (%) · pre‐existing and new‐onset diabetes in kidney transplant recipients
1 finding from 1 review