Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Hepato-Biliary

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 66.7%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Initial infusion rate of intravenous acetylcysteine over 15 minutes vs 60 minutes

All‐cause mortality · people with paracetamol (acetaminophen) overdose

1 finding from 1 review

Interventions for paracetamol (acetaminophen) overdose 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 180 participants
Very low

Initial infusion rate of intravenous acetylcysteine over 15 minutes vs 60 minutes

Hepatotoxicity · people with paracetamol (acetaminophen) overdose

It is very uncertain whether initial infusion rate of intravenous acetylcysteine over 15 minutes changes hepatotoxicity compared with 60 minutes (very low certainty).

1 finding from 1 review

Interventions for paracetamol (acetaminophen) overdose 2018 · Cochrane Headline outcomes only
OR 1.34 [0.39, 4.56]
1 study · 175 participants
Very low

Initial infusion rate of intravenous acetylcysteine over 15 minutes vs 60 minutes

Any adverse event · people with paracetamol (acetaminophen) overdose

Initial infusion rate of intravenous acetylcysteine over 15 minutes may leads to lower any adverse event compared with 60 minutes (low certainty).

1 finding from 1 review

Interventions for paracetamol (acetaminophen) overdose 2018 · Cochrane Headline outcomes only
OR 0.51 [0.27, 0.96]
1 study · 180 participants
Low