What do systematic reviews say?

Immediate treatment vs controls

Immediate treatment showed no clear difference in five‐year remission at any time after randomisation compared with controls (high certainty).

• Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure 2021 · Cochrane Headline outcomes only
  RR 1.02 [0.87, 1.21]
  2 studies · 1212 participants
  High