Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews

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No studies found 2 · 28.6%GRADE not reported 0 · 0%Very low 4 · 57.1%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%

Idebenone vs placebo

Change in Ejection fraction (%) · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low

Idebenone vs placebo

Change in cardiac function (change in peak systolic radial strain in LV lateral wall segments) · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

Idebenone vs placebo

Change in cardiac function (change in systolic radial strain rate LV inferolateral wall) · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

Idebenone vs placebo

Size of metabolically abnormal areas of myocardium · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Idebenone vs placebo

Improvements in quality of life measures · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Idebenone vs placebo

Adverse events · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Low

Idebenone vs placebo

Change in cardiac function (change in fractional shortening) · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low