Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews · Neuromuscular

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 2 · 66.7%Very low 0 · 0%Low 0 · 0%Moderate 1 · 33.3%High 0 · 0%

Idebenone vs placebo

Quality of life Assessed by: Pediatric Quality of Life Inventory, change from baseline (0 to 100; 0 = worst outcome, 100 = best outcome) · people with Duchenne muscular dystrophy and progressive respiratory decline

1 finding from 1 review

Antioxidants to prevent respiratory decline in people with Duchenne muscular dystrophy and progressive respiratory… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 63 participants
Moderate

Idebenone vs placebo

Longer‐term (minimum 1 month) change in generic quality of life scores · people with speech disorder resulting from hereditary ataxias

1 finding from 1 review

Treatment for speech disorder in Friedreich ataxia and other hereditary ataxia syndromes 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Idebenone vs placebo

Longer‐term burdens (minimum 1 month) (for example, demands on caregivers, frequency of tests, restrictions on lifestyle) · people with speech disorder resulting from hereditary ataxias

1 finding from 1 review

Treatment for speech disorder in Friedreich ataxia and other hereditary ataxia syndromes 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported