Ibuprofen taken pre-emptively (about 1 hour before treatment) vs Ibuprofen taken post-treatment
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
It is very uncertain whether ibuprofen taken pre-emptively (about 1 hour before treatment) changes pain intensity (VAS 0-100 mm) compared with ibuprofen taken post-treatment (very low certainty).
3 findings from 1 review
- Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes24 hoursMD -9.74 [-47.88, 28.40]2 studies · 69 participantsVery low
- Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes2 hoursMD -11.30 [-16.27, -6.33]1 study · 41 participantsVery low
- Pharmacological interventions for pain relief during orthodontic treatment 2017 · Cochrane All outcomes6 hoursMD -8.43 [-30.37, 13.50]2 studies · 69 participantsVery low