Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%

All‐cause mortality 12‐month · people with connective tissue disease‐associated interstitial lung disease

Cyclophosphamide showed no clear difference in all‐cause mortality 12‐month compared with mycophenolate (low certainty).

1 finding from 1 review

Cyclophosphamide for connective tissue disease–associated interstitial lung disease 2018 · Cochrane Headline outcomes only
OR 1.6 [0.65, 3.95]
2 studies · 187 participants
Low

All‐cause mortality 12‐month · people with connective tissue disease‐associated interstitial lung disease

Cyclophosphamide showed no clear difference in all‐cause mortality 12‐month compared with placebo (low certainty).

1 finding from 1 review

Cyclophosphamide for connective tissue disease–associated interstitial lung disease 2018 · Cochrane Headline outcomes only
OR 0.94 [0.19, 4.77]
2 studies · 179 participants
Low