Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

7 questions · 7 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 2 · 28.6%Very low 2 · 28.6%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%

IM pethidine vs placebo

Additional analgesia required (epidural, pethidine and Entonox) · women in labour

IM pethidine may leads to lower additional analgesia required (epidural, pethidine and Entonox) compared with placebo (low certainty).

1 finding from 1 review

IM pethidine vs placebo

Maternal satisfaction with analgesia measured during labour (number of women satisfied or very satisfied after 30 minutes) · women in labour

It is very uncertain whether IM pethidine changes maternal satisfaction with analgesia measured during labour (number… compared with placebo (very low certainty).

1 finding from 1 review

IM pethidine vs placebo

Maternal pain score or pain measured in labour (described as good or fair after 1 hour) · women in labour

IM pethidine may leads to higher maternal pain score or pain measured in labour (described as good or… compared with placebo (low certainty).

1 finding from 1 review

IM pethidine vs placebo

Maternal pain score or pain measured in labour (reduction in VAS of at least 40 mm after 30 minutes) · women in labour

IM pethidine may leads to higher maternal pain score or pain measured in labour (reduction in VAS of… compared with placebo (low certainty).

1 finding from 1 review

Patient-controlled analgesia (PCA) pethidine vs Staff-controlled delivery of pethidine

Daily mean opiate intake per hour · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis

Patient-controlled analgesia (PCA) pethidine showed no clear difference in daily mean opiate intake per hour compared with staff-controlled delivery of pethidine; GRADE not reported.

1 finding from 1 review

Patient-controlled analgesia (PCA) pethidine vs Staff-controlled delivery of pethidine

Average pain scores (0-100 VAS) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis

Patient-controlled analgesia (PCA) pethidine showed no clear difference in average pain scores (0-100 VAS) compared with staff-controlled delivery of pethidine; GRADE not reported.

1 finding from 1 review