Hydroxyapatite (e.g., nano-HAp) vs Calcium phosphate agent (e.g., CPP-ACP, Ca/P-PILP, niobophosphate)
Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)
In the Self-Etch adhesive + chemical ACAD protocol network, HAp showed 4.455 MPa lower 24 h bond strength than Calcium Phosphate (MD -4.455, 95% CI -8.857 to -0.053; Moderate certainty).
2 findings from 1 review
- Biomimetic Remineralization Strategies for Dentin Bond Stability-Systematic Review and Network Meta-Analysis. 2025 All outcomes24 h (immediate) · In vitro; extracted permanent human teeth; bond strength testing (SBS/microSBS/microTBS) · Self-Etch + chemical ACADMD -4.455 [-8.857, -0.053]0 studiesModerate
- Biomimetic Remineralization Strategies for Dentin Bond Stability-Systematic Review and Network Meta-Analysis. 2025 All outcomes24 h (immediate) · In vitro; extracted permanent human teeth; bond strength testing (SBS/microSBS/microTBS) · Etch-and-Rinse + chemical ACADMD 3.736 [-3.063, 0.536]0 studiesLow