Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

35 questions · 51 findings · 4 reviews

No studies found 0 · 0%GRADE not reported 18 · 35.3%Very low 13 · 25.5%Low 12 · 23.5%Moderate 2 · 3.9%High 6 · 11.8%

Highest vs lowest selenium exposure

Any cancer risk No. of participants: 19,475 (3 RCTs) · Participants in trials with low risk of bias

Highest showed no clear difference in any cancer risk No. of participants: 19,475 (3 RCTs) compared with lowest selenium exposure (high certainty).

1 finding from 1 review

Highest vs lowest selenium exposure

Mortality: all cancers · Participants in non experimental cohort studies on selenium and cancer

It is very uncertain whether highest changes cancer mortality risk No. of participants: 183,863 (7 observational… compared with lowest selenium exposure (very low certainty).

1 finding from 1 review