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Evidence found and GRADE certainty

6 questions · 6 findings · 1 reviews · All outcomes

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No studies found 0 · 0%GRADE not reported 6 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Higher maternal circulating 25-hydroxyvitamin D (25(OH)D) concentration vs Lower maternal circulating 25-hydroxyvitamin D (25(OH)D) concentration

Small‐for‐gestational age · pregnant women and their infants..

Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Small for gestational age: OR 0.54 (95% CI 0.44 to 0.67), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.

1 finding from 1 review

Higher maternal circulating 25-hydroxyvitamin D (25(OH)D) concentration vs Lower maternal circulating 25-hydroxyvitamin D (25(OH)D) concentration

Pre‐eclampsia · pregnant women and their infants..

Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Pre-eclampsia: OR 0.56 (95% CI 0.39 to 0.80), statistically significant. Umbrella review outcome-level evidence grade: No conclusion.

1 finding from 1 review

Higher maternal circulating 25-hydroxyvitamin D (25(OH)D) concentration vs Lower maternal circulating 25-hydroxyvitamin D (25(OH)D) concentration

Head circumference (mm) · pregnant women and their infants..

Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Head circumference: WMD 0.05 (95% CI -0.24 to 0.34), not statistically significant. Umbrella review outcome-level evidence grade: Suggestive.

1 finding from 1 review

Higher maternal circulating 25-hydroxyvitamin D (25(OH)D) concentration vs Lower maternal circulating 25-hydroxyvitamin D (25(OH)D) concentration

Birth length · pregnant women and their infants..

Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Birth length: WMD 0.19 (95% CI -0.26 to 0.65), not statistically significant. Umbrella review outcome-level evidence grade: Substantial effect unlikely.

1 finding from 1 review

Higher maternal circulating 25-hydroxyvitamin D (25(OH)D) concentration vs Lower maternal circulating 25-hydroxyvitamin D (25(OH)D) concentration

Birthweight (g) · pregnant women and their infants..

Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Birth weight: WMD 130.9 (95% CI 75.1 to 186.7), statistically significant. Umbrella review outcome-level evidence grade: Probable.

1 finding from 1 review

Higher maternal circulating 25-hydroxyvitamin D (25(OH)D) concentration vs Lower maternal circulating 25-hydroxyvitamin D (25(OH)D) concentration

Gestational diabetes · pregnant women and their infants..

Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Gestational diabetes: OR 0.67 (95% CI 0.53 to 0.85), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.

1 finding from 1 review