Findings

What do systematic reviews say?

2 questions · 3 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Higher circulating 25-hydroxyvitamin D (25(OH)D) concentration vs Lower circulating 25-hydroxyvitamin D (25(OH)D) concentration

Stroke · Adults (general population)

Meta-analysis of observational studies (higher vs lower 25(OH)D) for Stroke: RR 0.61 (95% CI 0.50 to 0.75), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.

1 finding from 1 review

Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational… 2014 All outcomes
RR 0.61 [0.50, 0.75]
7 studies · 39095 participants
GRADE not reported

Higher circulating 25-hydroxyvitamin D (25(OH)D) concentration vs Lower circulating 25-hydroxyvitamin D (25(OH)D) concentration

Ischaemic stroke · Adults (general population)

Meta-analysis of observational studies (higher vs lower 25(OH)D) for Ischaemic stroke (Hazard ratio (cohort studies)): HR 0.66 (95% CI 0.55 to 0.80), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.

2 findings from 1 review

Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational… 2014 All outcomes
Hazard ratio (cohort studies)
HR 0.66 [0.55, 0.80]
4 studies · 26596 participants
GRADE not reported
Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational… 2014 All outcomes
Odds ratio (case-control studies)
OR 0.52 [0.44, 0.61]
5 studies · 31858 participants
GRADE not reported