Evidence Gaps

What do systematic reviews say?

1 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Higher circulating 25-hydroxyvitamin D (25(OH)D) concentration vs Lower circulating 25-hydroxyvitamin D (25(OH)D) concentration

Depression · Adults (general population)

Meta-analysis of observational studies (higher vs lower 25(OH)D) for Depression (Cohort studies): HR 0.44 (95% CI 0.27 to 0.72), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.

2 findings from 1 review

Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational… 2014 All outcomes
Cohort studies
HR 0.44 [0.27, 0.72]
3 studies · 8815 participants
GRADE not reported
Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational… 2014 All outcomes
Case-control studies
OR 0.77 [0.59, 1.00]
9 studies · 19807 participants
GRADE not reported