High‐dose vs low‐dose colchicine
Pain ‐ not reported · acute gout
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
7 questions · 7 findings · 1 reviews · Musculoskeletal
No studies found 3 · 42.9%GRADE not reported 2 · 28.6%Very low 0 · 0%Low 2 · 28.6%Moderate 0 · 0%High 0 · 0%
High‐dose vs low‐dose colchicine
Participant global assessment of treatment success: proportion with 50% or greater decrease in pain score from baseline ‐ 32 to 36 hours · acute gout
High‐dose showed no clear difference in participant global assessment of treatment success: proportion with… compared with low‐dose colchicine (low certainty).
1 finding from 1 review
- RR 0.87 [0.56, 1.36]1 study · 126 participantsLow
High‐dose vs low‐dose colchicine
Reduction of inflammation ‐ not measured · acute gout
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
High‐dose vs low‐dose colchicine
Function of target joint ‐ not measured · acute gout
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
High‐dose vs low‐dose colchicine
Serious adverse events · acute gout
1 finding from 1 review
- no estimate extracted1 study · 126 participantsGRADE not reported
High‐dose vs low‐dose colchicine
Total adverse events · acute gout
High‐dose may leads to higher total adverse events compared with low‐dose colchicine (low certainty).
1 finding from 1 review
- RR 2.11 [1.51, 2.95]1 study · 126 participantsLow
High‐dose vs low‐dose colchicine
Withdrawals due to adverse events · acute gout
1 finding from 1 review
- no estimate extracted1 study · 126 participantsGRADE not reported