HEMA/EGDMA-based desensitizer vs Calcium phosphate agent (e.g., CPP-ACP, Ca/P-PILP, niobophosphate)
Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)
In the Self-Etch adhesive + chemical ACAD protocol network, HEMA vs Calcium Phosphate showed no significant difference in 24 h bond strength (MD 0.360, 95% CI -5.589 to 6.309; Moderate certainty).
1 finding from 1 review
- Biomimetic Remineralization Strategies for Dentin Bond Stability-Systematic Review and Network Meta-Analysis. 2025 All outcomes24 h (immediate) · In vitro; extracted permanent human teeth; bond strength testing (SBS/microSBS/microTBS) · Self-Etch + chemical ACADMD 0.360 [-5.589, 6.309]0 studiesModerate