Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 1 · 20%Very low 0 · 0%Low 0 · 0%Moderate 4 · 80%High 0 · 0%

H. pylori eradication therapy vs control

Incidence of gastric cancer ‐ modified ITT analysis Histological examination · healthy asymptomatic H. pylori‐infected individuals

H. pylori eradication therapy probably leads to lower incidence of gastric cancer ‐ modified ITT analysisHistological… compared with control (moderate certainty).

1 finding from 1 review

Helicobacter pylori eradication for the prevention of gastric neoplasia 2020 · Cochrane Headline outcomes only
RR 0.54 [0.4, 0.72]
7 studies · 8323 participants
Moderate

H. pylori eradication therapy vs control

Death from gastric cancer ‐ modified ITT analysis · healthy asymptomatic H. pylori‐infected individuals

H. pylori eradication therapy probably leads to lower death from gastric cancer ‐ modified ITT analysis compared with control (moderate certainty).

1 finding from 1 review

Helicobacter pylori eradication for the prevention of gastric neoplasia 2020 · Cochrane Headline outcomes only
RR 0.61 [0.4, 0.92]
4 studies · 6301 participants
Moderate

H. pylori eradication therapy vs control

Death Analysis 1.1 · healthy asymptomatic H. pylori‐infected individuals

H. pylori eradication therapy showed no clear difference in death from all causes ‐ modified ITT analysis compared with control (moderate certainty).

1 finding from 1 review

Helicobacter pylori eradication for the prevention of gastric neoplasia 2020 · Cochrane Headline outcomes only
RR 0.97 [0.85, 1.12]
5 studies · 7079 participants
Moderate

H. pylori eradication therapy vs control

Incidence of oesophageal squamous cell carcinoma ‐ modified ITT analysis · healthy asymptomatic H. pylori‐infected individuals

H. pylori eradication therapy showed no clear difference in incidence of oesophageal squamous cell carcinoma ‐ modified ITT… compared with control (moderate certainty).

1 finding from 1 review

Helicobacter pylori eradication for the prevention of gastric neoplasia 2020 · Cochrane Headline outcomes only
RR 1.22 [0.59, 2.54]
2 studies · 3888 participants
Moderate

H. pylori eradication therapy vs control

Adverse events · healthy asymptomatic H. pylori‐infected individuals

1 finding from 1 review

Helicobacter pylori eradication for the prevention of gastric neoplasia 2020 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported