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Evidence found and GRADE certainty

4 questions · 4 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 4 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Grape seed extract or grape seed flavonoid fractions vs No extract or vehicle control; other antimicrobial agents

Biofilm morphology · Streptococcus mutans (in vitro cultures and biofilms)

No meta-analysis was conducted; two included studies reported reduced microcolonies or altered bacterial structure with grape seed extract.

1 finding from 1 review

Grape seed extract or grape seed flavonoid fractions vs No extract or vehicle control; other antimicrobial agents

Bacterial growth inhibition · Streptococcus mutans (in vitro cultures and biofilms)

No meta-analysis was conducted; five included studies reported inhibition of Streptococcus mutans growth with grape seed extract or fractions.

1 finding from 1 review

Grape seed extract or grape seed flavonoid fractions vs No extract or vehicle control; other antimicrobial agents

Cell damage or cytotoxicity · Streptococcus mutans (in vitro cultures and biofilms)

No meta-analysis was conducted; one included study reported very low cell damage with grape seed extract.

1 finding from 1 review

Grape seed extract or grape seed flavonoid fractions vs No extract or vehicle control; other antimicrobial agents

Bacterial adhesion · Streptococcus mutans (in vitro cultures and biofilms)

No meta-analysis was conducted; two included studies reported reduced Streptococcus mutans adhesion with grape seed extract or fractions.

1 finding from 1 review