What do systematic reviews say?

Gonadotrophins vs continued clomiphene citrate

Gonadotrophins probably leads to higher live birth rate per woman compared with continued clomiphene citrate (moderate certainty).

• Gonadotrophins for ovulation induction in women with polycystic ovary syndrome 2019 · Cochrane Headline outcomes only
  RR 1.24 [1.05, 1.46]
  1 study · 661 participants
  Moderate

Gonadotrophins vs continued clomiphene citrate

Gonadotrophins showed no clear difference in incidence of multiple pregnancy per woman compared with continued clomiphene citrate (moderate certainty).

• Gonadotrophins for ovulation induction in women with polycystic ovary syndrome 2019 · Cochrane Headline outcomes only
  RR 0.89 [0.33, 2.4]
  1 study · 661 participants
  Moderate

Gonadotrophins vs continued clomiphene citrate

Gonadotrophins probably leads to higher clinical pregnancy rate per woman compared with continued clomiphene citrate (moderate certainty).

• Gonadotrophins for ovulation induction in women with polycystic ovary syndrome 2019 · Cochrane Headline outcomes only
  RR 1.31 [1.13, 1.52]
  1 study · 661 participants
  Moderate

Gonadotrophins vs continued clomiphene citrate

Gonadotrophins may leads to higher miscarriages per woman compared with continued clomiphene citrate (low certainty).

• Gonadotrophins for ovulation induction in women with polycystic ovary syndrome 2019 · Cochrane Headline outcomes only
  RR 2.23 [1.11, 4.47]
  1 study · 661 participants
  Low

Gonadotrophins vs continued clomiphene citrate

• Gonadotrophins for ovulation induction in women with polycystic ovary syndrome 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 661 participants
  Low