GnRH agonist plus chemotherapy vs chemotherapy alone
Adverse effects: vaginal dryness · premenopausal women with malignant conditions, receiving GnRH agonist before or in parallel to chemotherapy
GnRH agonist plus chemotherapy showed no clear difference in adverse effects: vaginal dryness compared with chemotherapy alone (moderate certainty).
1 finding from 1 review
- Adjuvant gonadotropin‐releasing hormone analogues for the prevention of chemotherapy‐induced premature ovarian failure… 2019 · Cochrane Headline outcomes onlyRR 1.18 [0.68, 2.04]2 studies · 488 participantsModerate