Fondaparinux vs placebo
Fondaparinux probably leads to lower symptomatic VTE Ventilation‐perfusion scanning, helical computed… compared with placebo (moderate certainty).
- RR 0.15 [0.04, 0.5]1 study · 3002 participantsModerate
Fondaparinux probably leads to lower symptomatic VTE Ventilation‐perfusion scanning, helical computed… compared with placebo (moderate certainty).
Fondaparinux showed no clear difference in major bleeding compared with placebo (moderate certainty).
Fondaparinux probably leads to lower extension of ST Ultrasonography compared with placebo (moderate certainty).
Fondaparinux probably leads to lower recurrence of ST Ultrasonography compared with placebo (moderate certainty).
Fondaparinux showed no clear difference in mortality compared with placebo (moderate certainty).
Fondaparinux showed no clear difference in minor bleeding compared with placebo (moderate certainty).
Fondaparinux showed no clear difference in adverse effects of treatment compared with placebo (moderate certainty).
Fondaparinux probably leads to lower total VTE compared with placebo (moderate certainty).
Fondaparinux probably leads to lower total DVT compared with LMWH (moderate certainty).
Fondaparinux showed no clear difference in proximal DVT compared with LMWH (low certainty).
Fondaparinux showed no clear difference in total PE compared with LMWH (moderate certainty).
Fondaparinux leads to higher major bleeding compared with LMWH (high certainty).
Fondaparinux showed no clear difference in all causes of death compared with LMWH (moderate certainty).
Fondaparinux leads to lower symptomatic VTE compared with placebo (high certainty).
It is very uncertain whether fondaparinux changes major bleeding compared with variable dose warfarin (very low certainty).