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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews

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Summary of findings: Folic acid vs placebo

Liver toxicity (incidence of transaminase elevation) · Patients receiving methotrexate for rheumatoid arthritis

Folic acid probably leads to lower liver toxicity (ie, incidence of transaminase elevation) compared with placebo (moderate certainty).

1 finding from 1 review

Folic or folinic acid (any) vs placebo

Liver toxicity (incidence of transaminase elevation) · Patients receiving methotrexate for rheumatoid arthritis

Folic or folinic acid (any) probably leads to lower liver toxicity (incidence of transaminase elevation) compared with placebo (moderate certainty).

1 finding from 1 review