Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 1 · 20%Very low 0 · 0%Low 0 · 0%Moderate 4 · 80%High 0 · 0%

Failure to respond (reduction ≥ 50% on HDRS) · patients with depression

Fluoxetine showed no clear difference in failure to respond (reduction ≥ 50% on HDRS) compared with bupropion (moderate certainty).

1 finding from 1 review

Fluoxetine versus other types of pharmacotherapy for depression 2013 · Cochrane Headline outcomes only
OR 0.83 [0.48, 1.43]
2 studies · 436 participants
Moderate

Endpoint score (HDRS or MADRS) · patients with depression

1 finding from 1 review

Fluoxetine versus other types of pharmacotherapy for depression 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Failure to complete ‐ total ‐ · patients with depression

Fluoxetine showed no clear difference in failure to complete ‐ total ‐ compared with bupropion (moderate certainty).

1 finding from 1 review

Fluoxetine versus other types of pharmacotherapy for depression 2013 · Cochrane Headline outcomes only
OR 1 [0.67, 1.48]
2 studies · 436 participants
Moderate

Failure to complete ‐ inefficacy ‐ · patients with depression

Fluoxetine showed no clear difference in failure to complete ‐ inefficacy ‐ compared with bupropion (moderate certainty).

1 finding from 1 review

Fluoxetine versus other types of pharmacotherapy for depression 2013 · Cochrane Headline outcomes only
OR 1.16 [0.33, 4.1]
2 studies · 436 participants
Moderate

Failure to complete ‐ side effects ‐ · patients with depression

Fluoxetine showed no clear difference in failure to complete ‐ side effects ‐ compared with bupropion (moderate certainty).

1 finding from 1 review

Fluoxetine versus other types of pharmacotherapy for depression 2013 · Cochrane Headline outcomes only
OR 1.01 [0.45, 2.25]
2 studies · 436 participants
Moderate