Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Overall adverse events 5 weeks · adults with seasonal affective disorder

It is very uncertain whether fluoxetine changes overall adverse events 5 weeks compared with placebo (very low certainty).

1 finding from 1 review

Second‐generation antidepressants for treatment of seasonal affective disorder 2021 · Cochrane Headline outcomes only
RR 1.07 [0.95, 1.21]
1 study · 68 participants
Very low

Adverse events ‐ treatment emergent · adults with seasonal affective disorder

Fluoxetine showed no clear difference in adverse events (at least 1 treatment‐emergent adverse event) compared with light therapy (low certainty).

1 finding from 1 review

Second‐generation antidepressants for treatment of seasonal affective disorder 2021 · Cochrane Headline outcomes only
RR 0.97 [0.78, 1.22]
1 study · 96 participants
Low