Fluoride varnish applied before 4 years of age vs Non-fluoride (placebo) varnish
Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years
Fluoride varnish applied before 4 years of age (biannual) showed no clear difference in fluorosis (percentage prevalence in permanent teeth) compared with placebo varnish (low certainty).
1 finding from 1 review
- Topical fluoride as a cause of dental fluorosis in children 2024 · Cochrane All outcomesFluorosis assessed when most permanent teeth of interest had erupted (6 to 18 years)RR 0.77 [0.45, 1.31]1 study · 123 participantsLow