Fluoride varnish applied before 4 years of age vs No fluoride varnish application
Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years
Fluoride varnish applied before 4 years of age may leads to higher fluorosis (percentage prevalence in permanent teeth) compared with no fluoride varnish application (low certainty).
1 finding from 1 review
- Topical fluoride as a cause of dental fluorosis in children 2024 · Cochrane All outcomesFluorosis assessed when most permanent teeth of interest had erupted (6 to 18 years)OR 2.18 [1.46, 3.25]2 studies · 982 participantsLow