Fluoride toothpaste less than 1000 ppm (lower concentration) vs Fluoride toothpaste 1000 ppm or more (higher concentration)
Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years
It is very uncertain whether fluoride toothpaste less than 1000 ppm (lower concentration) changes fluorosis (percentage prevalence in permanent teeth) compared with fluoride toothpaste 1000 ppm or more (higher concentration) (very low certainty).
2 findings from 1 review
- Topical fluoride as a cause of dental fluorosis in children 2024 · Cochrane All outcomesFluorosis assessed when most permanent teeth of interest had erupted (6 to 18 years)OR 0.89 [0.52, 1.52]2 studies · 258 participantsVery low
- Topical fluoride as a cause of dental fluorosis in children 2024 · Cochrane All outcomesFluorosis assessed when most permanent teeth of interest had erupted (6 to 18 years)OR 0.79 [0.62, 1.02]3 studies · 2037 participantsVery low