Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

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No studies found 3 · 75%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

First‐line thiazides vs ACE inhibitor

Total serious adverse events · patients with hypertension

The review found no eligible studies for this question.

1 finding from 1 review

First‐line diuretics versus other classes of antihypertensive drugs for hypertension 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

First‐line thiazides vs beta‐blocker

Total serious adverse events · patients with hypertension

The review found no eligible studies for this question.

1 finding from 1 review

First‐line diuretics versus other classes of antihypertensive drugs for hypertension 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

First‐line thiazides vs alpha‐blocker

Total serious adverse events · patients with hypertension

The review found no eligible studies for this question.

1 finding from 1 review

First‐line diuretics versus other classes of antihypertensive drugs for hypertension 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

First‐line thiazides vs calcium channel blockers

Total serious adverse events Duration: 1.75 to 3 years · patients with hypertension

First‐line thiazides showed no clear difference in total serious adverse events Duration: 1.75 to 3 years compared with first‐line calcium channel blockers (low certainty).

1 finding from 1 review

First‐line diuretics versus other classes of antihypertensive drugs for hypertension 2023 · Cochrane Headline outcomes only
RR 1.09 [0.97, 1.24]
2 studies · 7204 participants
Low