Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

35 questions · 36 findings · 3 reviews

No studies found 8 · 22.2%GRADE not reported 4 · 11.1%Very low 12 · 33.3%Low 9 · 25%Moderate 3 · 8.3%High 0 · 0%

Fibrinolytics vs placebo

Overall treatment failure, including mortality, thoracic surgery or referral for further fibrinolytic therapy · adult parapneumonic effusions and empyema

It is very uncertain whether fibrinolytics changes overall treatment failure, including mortality, thoracic surgery or… compared with placebo (very low certainty).

1 finding from 1 review

Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs levonorgestrel intrauterine system

Menstrual blood loss: improvement in mean blood loss (PBAC score < 100) · heavy menstrual bleeding

It is very uncertain whether antifibrinolytics changes menstrual blood loss: improvement in mean blood loss (PBAC score <… compared with levonorgestrel intrauterine system (very low certainty).

1 finding from 1 review