Findings

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5 questions · 5 findings · 1 reviews

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No studies found 1 · 20%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 4 · 80%High 0 · 0%

Fexofenadine 120 mg/d vs placebo (1‐week intervention)

Pruritus · adults with eczema

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 400 participants
Moderate

Fexofenadine 120 mg/d vs placebo (1‐week intervention)

Primary outcome 2. Proportion of participants reporting adverse effects and serious adverse events throughout the study period · adults with eczema

Fexofenadine 120 mg/d showed no clear difference in primary outcome 2. Proportion of participants reporting adverse… compared with placebo (1‐week intervention) (moderate certainty).

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
RR 1.05 [0.74, 1.5]
1 study · 411 participants
Moderate

Fexofenadine 120 mg/d vs placebo (1‐week intervention)

Secondary outcome 1. Mean change in physician‐assessed clinical signs This outcome was assessed as investigator‐assessed change in the ratio of pruritus area to body surface area · adults with eczema

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Moderate

Fexofenadine 120 mg/d vs placebo (1‐week intervention)

Secondary outcome: quality of life · adults with eczema

The review found no eligible studies for this question.

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Fexofenadine 120 mg/d vs placebo (1‐week intervention)

Secondary outcome 3. Number of eczema flares, measured by, for example, ‘escalation of treatment’ or ‘use of topical anti‐inflammatory medications’ Amount of 0.1% hydrocortisone butyrate cream used during the study · adults with eczema

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Moderate