Findings

What do systematic reviews say?

6 questions · 9 findings · 1 reviews · Heart

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 11.1%High 8 · 88.9%

All causes of mortality at 30 days · Anticoagulants in ACS

Factor Xa inhibitors showed no clear difference in all causes of mortality at 30 days compared with anticoagulants (high certainty).

1 finding from 1 review

Factor Xa inhibitors for acute coronary syndromes 2011 · Cochrane Headline outcomes only
RR 0.9 [0.8, 1.01]
4 studies · 27976 participants
High

All causes of mortality at 30 days ‐ UFH · Anticoagulants in ACS

Factor Xa inhibitors showed no clear difference in all causes of mortality at 30 days ‐ UFH compared with anticoagulants (high certainty).

1 finding from 1 review

Factor Xa inhibitors for acute coronary syndromes 2011 · Cochrane Headline outcomes only
RR 0.98 [0.82, 1.18]
2 studies · 6760 participants
High

All causes of mortality at 30 days ‐ Enoxaparin · Anticoagulants in ACS

Factor Xa inhibitors leads to lower all causes of mortality at 30 days ‐ Enoxaparin compared with anticoagulants (high certainty).

1 finding from 1 review

Factor Xa inhibitors for acute coronary syndromes 2011 · Cochrane Headline outcomes only
RR 0.85 [0.73, 0.98]
2 studies · 21216 participants
High

Major bleeding · Anticoagulants in ACS

Factor Xa inhibitors showed no clear difference in major bleeding at 30 days compared with anticoagulants (high certainty).

2 findings from 1 review

Factor Xa inhibitors for acute coronary syndromes 2011 · Cochrane Headline outcomes only
RR 1.01 [0.98, 1.04]
2 studies · 20404 participants
High
Factor Xa inhibitors for acute coronary syndromes 2011 · Cochrane Headline outcomes only
RR 0.98 [0.92, 1.04]
1 study · 326 participants
High

Major bleeding at 30 days ‐ Enoxaparin · Anticoagulants in ACS

Factor Xa inhibitors leads to higher major bleeding at 30 days ‐ Enoxaparin compared with anticoagulants (high certainty).

1 finding from 1 review

Factor Xa inhibitors for acute coronary syndromes 2011 · Cochrane Headline outcomes only
RR 1.02 [1.01, 1.02]
1 study · 20078 participants
High

Minor bleeding · Anticoagulants in ACS

Factor Xa inhibitors showed no clear difference in minor bleeding at 30 days compared with anticoagulants (high certainty).

3 findings from 1 review

Factor Xa inhibitors for acute coronary syndromes 2011 · Cochrane Headline outcomes only
RR 0.7 [0.14, 3.39]
2 studies · 20404 participants
High
Factor Xa inhibitors for acute coronary syndromes 2011 · Cochrane Headline outcomes only
RR 1.76 [0.52, 5.94]
1 study · 326 participants
Moderate
Factor Xa inhibitors for acute coronary syndromes 2011 · Cochrane Headline outcomes only
RR 0.34 [0.28, 0.43]
1 study · 20078 participants
High