Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

42 questions · 42 findings · 3 reviews

No studies found 16 · 38.1%GRADE not reported 12 · 28.6%Very low 6 · 14.3%Low 8 · 19%Moderate 0 · 0%High 0 · 0%

FLUPENTHIXOL DECANOATE vs other depot antipsychotic drugs

Clinical response: global state ‐ no clinical improvement ‐ short term Rates of improvement · patients with schizophrenia or related psychoses

FLUPENTHIXOL DECANOATE showed no clear difference in clinical response: global state ‐ no clinical improvement ‐ short… compared with OTHER DEPOT ANTIPSYCHOTICS (low certainty).

1 finding from 1 review

FLUPENTHIXOL DECANOATE vs other depot antipsychotic drugs

Leaving the study early ‐ short/medium term Rate of attrition · patients with schizophrenia or related psychoses

FLUPENTHIXOL DECANOATE showed no clear difference in leaving the study early ‐ short/medium term Rate of attrition compared with OTHER DEPOT ANTIPSYCHOTICS (low certainty).

1 finding from 1 review

FLUPENTHIXOL DECANOATE vs other depot antipsychotic drugs

Adverse effects: general ‐ movement disorders ‐ requiring anticholinergic medication ‐ short/medium term Numbers requiring anticholinergic medication · patients with schizophrenia or related psychoses

FLUPENTHIXOL DECANOATE showed no clear difference in adverse effects: general ‐ movement disorders ‐ requiring… compared with OTHER DEPOT ANTIPSYCHOTICS (low certainty).

1 finding from 1 review

FLUPENTHIXOL DECANOATE vs GENERAL ORAL ANTIPSYCHOTICS

Global state: Response ‐ proxy outcome ‐ mental state: 1. General ‐ average score (Brief Psychiatric Rating Scale by over 24 weeks · patients with schizophrenia or related psychoses

The review found no eligible studies for this question.

1 finding from 1 review

FLUPENTHIXOL DECANOATE vs GENERAL ORAL ANTIPSYCHOTICS

Leaving the study early ‐ short/medium term Rate of attrition · patients with schizophrenia or related psychoses

It is very uncertain whether FLUPENTHIXOL DECANOATE changes leaving the study early ‐ short term Rate of attrition compared with ORAL ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

FLUPENTHIXOL DECANOATE vs GENERAL ORAL ANTIPSYCHOTICS

Adverse effects: general ‐ movement disorders ‐ requiring anticholinergic medication ‐ short term Numbers requiring anticholinergic medication · patients with schizophrenia or related psychoses

It is very uncertain whether FLUPENTHIXOL DECANOATE changes adverse effects: general ‐ movement disorders ‐ requiring… compared with ORAL ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

FLUPENTHIXOL DECANOATE vs other depot antipsychotic drugs

Clinical response: mental state ‐ relapse ‐ medium term Relapse rate · patients with schizophrenia or related psychoses

FLUPENTHIXOL DECANOATE showed no clear difference in clinical response: mental state ‐ relapse ‐ medium term Relapse rate compared with OTHER DEPOT ANTIPSYCHOTICS (low certainty).

1 finding from 1 review

FLUPENTHIXOL DECANOATE VERY LOW (˜6 mg/IM) DOSE vs FLUPENTHIXOL DECANOATE LOW DOSE (˜9 mg/IM)

Clinical response: mental state ‐ relapse ‐ medium term Relapse rate · patients with schizophrenia or related psychoses

FLUPENTHIXOL DECANOATE VERY LOW (˜6 mg/IM) DOSE showed no clear difference in clinical response: mental state ‐ relapse ‐ medium term Relapse rate compared with FLUPENTHIXOL DECANOATE LOW DOSE (˜9 mg/IM) (low certainty).

1 finding from 1 review