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What do systematic reviews say?

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Evidence found and GRADE certainty

14 questions · 14 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 2 · 14.3%Very low 7 · 50%Low 4 · 28.6%Moderate 1 · 7.1%High 0 · 0%

FAE vs placebo

PASI score (scale range from 0 to 72 (higher score indicates more severe psoriasis)) · psoriasis
1 finding from 1 review

FAE vs MTX

Common nuisance AEs (not leading to treatment discontinuation) · psoriasis

It is very uncertain whether FAE changes common nuisance AEs (not leading to treatment discontinuation) compared with MTX (very low certainty).

1 finding from 1 review

FAE vs MTX

PASI 50 · psoriasis

It is very uncertain whether FAE changes PASI 50 compared with MTX (very low certainty).

1 finding from 1 review

FAE vs MTX

Percentage of participants reaching PASI 75 · psoriasis

It is very uncertain whether FAE changes PASI 75 compared with MTX (very low certainty).

1 finding from 1 review

FAE vs MTX

PASI 90 · psoriasis

It is very uncertain whether FAE changes PASI 90 compared with MTX (very low certainty).

1 finding from 1 review

FAE vs placebo

Common nuisance AEs (not leading to treatment discontinuation) · psoriasis

FAE probably leads to higher common nuisance AEs (not leading to treatment discontinuation) compared with placebo (moderate certainty).

1 finding from 1 review

FAE vs MTX

PASI score (scale range from 0 to 72 (higher score indicates more severe psoriasis)) · psoriasis
1 finding from 1 review

FAE vs MTX

Withdrawals due to adverse events · psoriasis

It is very uncertain whether FAE changes AEs leading to treatment discontinuation compared with MTX (very low certainty).

1 finding from 1 review