Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews · Skin

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 75%Low 0 · 0%Moderate 1 · 25%High 0 · 0%

Common nuisance AEs (not leading to treatment discontinuation) · psoriasis

It is very uncertain whether FAE changes common nuisance AEs (not leading to treatment discontinuation) compared with MTX (very low certainty).

1 finding from 1 review

Oral fumaric acid esters for psoriasis 2015 · Cochrane Headline outcomes only
RR 0.89 [0.77, 1.03]
1 study · 54 participants
Very low

Withdrawals due to adverse events · psoriasis

1 finding from 1 review

Oral fumaric acid esters for psoriasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 27 participants
Very low

Common nuisance AEs (not leading to treatment discontinuation) · psoriasis

FAE probably leads to higher common nuisance AEs (not leading to treatment discontinuation) compared with placebo (moderate certainty).

1 finding from 1 review

Oral fumaric acid esters for psoriasis 2015 · Cochrane Headline outcomes only
RR 4.72 [2.45, 9.08]
1 study · 99 participants
Moderate

Withdrawals due to adverse events · psoriasis

It is very uncertain whether FAE changes AEs leading to treatment discontinuation compared with MTX (very low certainty).

1 finding from 1 review

Oral fumaric acid esters for psoriasis 2015 · Cochrane Headline outcomes only
RR 0.19 [0.02, 1.53]
1 study · 51 participants
Very low