Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Myocardial infarction · people at high risk of CVD (history of CVD or high LDL‐C despite treatment)

It is very uncertain whether evolocumab changes myocardial infarction compared with ezetimibe and statins (very low certainty).

1 finding from 1 review

PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease 2020 · Cochrane Headline outcomes only
OR 0.66 [0.23, 1.85]
3 studies · 5003 participants
Very low