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Evidence found and GRADE certainty

7 questions · 7 findings · 1 reviews

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No studies found 1 · 14.3%GRADE not reported 0 · 0%Very low 1 · 14.3%Low 3 · 42.9%Moderate 1 · 14.3%High 1 · 14.3%

Escalated BEACOPP vs chemotherapy including ABVD

Relapse, progression or death (calculated instead of PFS) · Patients with early unfavourable or advanced stage HL

Escalated BEACOPP probably leads to lower progression, relapse or death compared with chemotherapy including ABVD (moderate certainty).

1 finding from 1 review

Escalated BEACOPP vs chemotherapy including ABVD

Adverse event: treatment‐related mortality · Patients with early unfavourable or advanced stage HL

Escalated BEACOPP showed no clear difference in adverse event: treatment‐related mortality compared with chemotherapy including ABVD (low certainty).

1 finding from 1 review

Escalated BEACOPP vs chemotherapy including ABVD

Adverse event: secondary malignancies · Patients with early unfavourable or advanced stage HL

Escalated BEACOPP showed no clear difference in adverse event: secondary malignancies compared with chemotherapy including ABVD (low certainty).

1 finding from 1 review

Escalated BEACOPP vs chemotherapy including ABVD

Adverse event: secondary malignancies: AML or MDS · Patients with early unfavourable or advanced stage HL

Escalated BEACOPP may leads to higher adverse event: secondary malignancies: AML or MDS compared with chemotherapy including ABVD (low certainty).

1 finding from 1 review

Escalated BEACOPP vs chemotherapy including ABVD

Adverse event: infertility (secondary amenorrhoea) · Patients with early unfavourable or advanced stage HL

It is very uncertain whether escalated BEACOPP changes adverse event: infertility (secondary amenorrhoea) compared with chemotherapy including ABVD (very low certainty).

1 finding from 1 review