Findings

What do systematic reviews say?

28 questions · 28 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 9 · 32.1%Very low 0 · 0%Low 5 · 17.9%Moderate 5 · 17.9%High 9 · 32.1%

Droperidol vs OLANZAPINE

Economic: direct costs · acute psychosis

1 finding from 1 review

Droperidol for psychosis‐induced aggression or agitation 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Droperidol vs placebo

Adverse effects ‐ cardiovascular ‐ arrhythmia · acute psychosis

Droperidol showed no clear difference in adverse effects ‐ cardiovascular ‐ arrhythmia compared with placebo (moderate certainty).

1 finding from 1 review

Droperidol for psychosis‐induced aggression or agitation 2016 · Cochrane Headline outcomes only
RR 0.34 [0.01, 8.31]
1 study · 227 participants
Moderate

Droperidol vs placebo

Adverse effects ‐ respiratory ‐ airway obstruction · acute psychosis

Droperidol showed no clear difference in adverse effects ‐ respiratory ‐ airway obstruction compared with placebo (low certainty).

1 finding from 1 review

Droperidol for psychosis‐induced aggression or agitation 2016 · Cochrane Headline outcomes only
RR 0.62 [0.15, 2.52]
1 study · 227 participants
Low

Droperidol vs placebo

Service use: person able to be discharged home · acute psychosis

Droperidol showed no clear difference in service use: person able to be discharged home compared with placebo (high certainty).

1 finding from 1 review

Droperidol for psychosis‐induced aggression or agitation 2016 · Cochrane Headline outcomes only
RR 1.16 [0.9, 1.48]
1 study · 227 participants
High

Droperidol vs placebo

Mental state ‐ improvement · acute psychosis

1 finding from 1 review

Droperidol for psychosis‐induced aggression or agitation 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Droperidol vs placebo

Economic: direct costs · acute psychosis

1 finding from 1 review

Droperidol for psychosis‐induced aggression or agitation 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Droperidol vs haloperidol

Tranquillisation or asleep · acute psychosis

Droperidol showed no clear difference in tranquillisation or asleep: tranquillised/sleep ‐ by around 30 minutes compared with haloperidol (high certainty).

1 finding from 1 review

Droperidol for psychosis‐induced aggression or agitation 2016 · Cochrane Headline outcomes only
RR 1.01 [0.93, 1.09]
1 study · 228 participants
High

Droperidol vs haloperidol

Global state: use of additional medication ‐ by 60 minutes after initial adequate sedation until ED discharge (various psychotropic drugs) · acute psychosis

Droperidol leads to lower global state: use of additional medication ‐ by 60 minutes after… compared with haloperidol (high certainty).

1 finding from 1 review

Droperidol for psychosis‐induced aggression or agitation 2016 · Cochrane Headline outcomes only
RR 0.37 [0.16, 0.9]
2 studies · 255 participants
High