Doxycycline 40 mg vs placebo
HRQOL ‐ not measured · Participants with rosacea
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
28 questions · 28 findings · 2 reviews · Skin
No studies found 9 · 32.1%GRADE not reported 0 · 0%Very low 0 · 0%Low 5 · 17.9%Moderate 4 · 14.3%High 10 · 35.7%
Doxycycline 40 mg vs placebo
Participant‐assessed improvement in rosacea severity ‐ not measured · Participants with rosacea
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Doxycycline 40 mg vs placebo
Proportion of participants with adverse event · Participants with rosacea
1 finding from 1 review
- no estimate extracted2 studies · 537 participantsHigh
Doxycycline 40 mg vs placebo
Physician‐assessed improvement in rosacea severity · Participants with rosacea
1 finding from 1 review
- no estimate extracted2 studies · 537 participantsHigh
Doxycycline 40 mg vs placebo
Assessment of erythema or telangiectasia · Participants with rosacea
1 finding from 1 review
- no estimate extracted2 studies · 537 participantsHigh
Doxycycline 40 mg vs placebo
Lesion count · Participants with rosacea
1 finding from 1 review
- no estimate extracted2 studies · 537 participantsModerate
Doxycycline 40 mg vs placebo
Time needed until improvement of the skin lesions · Participants with rosacea
1 finding from 1 review
- no estimate extracted2 studies · 537 participantsHigh
Doxycycline 40 mg vs placebo
Duration of remission ‐ not measured · Participants with rosacea
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel
Physician‐assessed improvement in rosacea severity · Participants with rosacea
Doxycycline 40 mg + azelaic acid gel showed no clear difference in physician‐assessed improvement in rosacea severity Investigator's… compared with doxycycline 40 mg + metronidazole gel (high certainty).
1 finding from 1 review
- RR 1.08 [0.93, 1.27]1 study · 207 participantsHigh
Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel
Clinician's Erythema Assessment ‐ not measured · Participants with rosacea
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel
Lesion count · Participants with rosacea
1 finding from 1 review
- no estimate extracted1 study · 207 participantsModerate
Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel
Time needed until improvement · Participants with rosacea
1 finding from 1 review
- no estimate extracted1 study · 207 participantsHigh
Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel
Duration of remission ‐ not measured · Participants with rosacea
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel
HRQOL ‐ not measured · Participants with rosacea
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel
Participant‐assessed improvement in rosacea severity · Participants with rosacea
Doxycycline 40 mg + azelaic acid gel showed no clear difference in participant‐assessed improvement in rosacea severity Excellent… compared with doxycycline 40 mg + metronidazole gel (high certainty).
1 finding from 1 review
- RR 1.05 [0.79, 1.4]1 study · 207 participantsHigh
Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel
Proportion of participants with adverse event · Participants with rosacea
Doxycycline 40 mg + azelaic acid gel showed no clear difference in proportion of participants with adverse event compared with doxycycline 40 mg + metronidazole gel (high certainty).
1 finding from 1 review
- RR 0.27 [0.06, 1.28]1 study · 207 participantsHigh
Doxycycline 40 mg + metronidazole 1% gel vs doxycycline 100 mg + metronidazole 1% gel
HRQOL ‐ not measured · Participants with rosacea
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Doxycycline 40 mg + metronidazole 1% gel vs doxycycline 100 mg + metronidazole 1% gel
Participant‐assessed improvement in rosacea severity ‐ not measured · Participants with rosacea
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Doxycycline 40 mg + metronidazole 1% gel vs doxycycline 100 mg + metronidazole 1% gel
Proportion of participants with adverse event · Participants with rosacea
Doxycycline 40 mg + metronidazole 1% gel may leads to lower proportion of participants with adverse event compared with doxycycline 100 mg + metronidazole 1% gel (low certainty).
1 finding from 1 review
- RR 0.25 [0.11, 0.54]1 study · 91 participantsLow
Doxycycline 40 mg + metronidazole 1% gel vs doxycycline 100 mg + metronidazole 1% gel
Physician‐assessed improvement in rosacea severity · Participants with rosacea
1 finding from 1 review
- no estimate extracted1 study · 91 participantsLow