Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

83 questions · 97 findings · 10 reviews

No studies found 24 · 24.7%GRADE not reported 28 · 28.9%Very low 11 · 11.3%Low 18 · 18.6%Moderate 6 · 6.2%High 10 · 10.3%

Mechanical debridement plus local antimicrobial (minocycline microspheres or doxycycline gel) vs Mechanical debridement alone

Probing pocket depth (PPD/PD) · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)

Mechanical debridement plus local antimicrobial (minocycline… showed no clear difference in pocket depth (mm) compared with mechanical debridement alone (low certainty).

1 finding from 1 review

Mechanical debridement plus local antimicrobial (minocycline microspheres or doxycycline gel) vs Mechanical debridement alone

Clinical attachment level (CAL) · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)

Mechanical debridement plus local antimicrobial (minocycline… showed no clear difference in clinical attachment level (mm) compared with mechanical debridement alone (low certainty).

1 finding from 1 review