Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

No studies found 1 · 20%GRADE not reported 0 · 0%Very low 2 · 40%Low 2 · 40%Moderate 0 · 0%High 0 · 0%

Recurrence of atrial fibrillation · adults in sinus rhythm after cardioversion of atrial fibrillation

Disopyramide showed no clear difference in recurrence of atrial fibrillation compared with placebo or no treatment (low certainty).

1 finding from 1 review

Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation 2019 · Cochrane Headline outcomes only
RR 0.77 [0.59, 1.01]
2 studies · 146 participants
Low

All‐cause mortality · adults in sinus rhythm after cardioversion of atrial fibrillation

It is very uncertain whether disopyramide changes all‐cause mortality compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation 2019 · Cochrane Headline outcomes only
RR 5 [0.25, 101.37]
1 study · 92 participants
Very low

Withdrawals due to adverse events · adults in sinus rhythm after cardioversion of atrial fibrillation

Disopyramide showed no clear difference in withdrawals due to adverse effects compared with placebo or no treatment (low certainty).

1 finding from 1 review

Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation 2019 · Cochrane Headline outcomes only
RR 3.68 [0.95, 14.24]
2 studies · 146 participants
Low

Proarrhythmia · adults in sinus rhythm after cardioversion of atrial fibrillation

The review found no eligible studies for this question.

1 finding from 1 review

Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Stroke · adults in sinus rhythm after cardioversion of atrial fibrillation

It is very uncertain whether disopyramide changes stroke compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation 2019 · Cochrane Headline outcomes only
RR 0.31 [0.03, 2.91]
2 studies · 146 participants
Very low