Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews

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No studies found 1 · 12.5%GRADE not reported 0 · 0%Very low 7 · 87.5%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Discontinuation by "tapering" vs usual family planning care

Successful discontinuation rate · participants with depressive or anxiety disorders

The review found no eligible studies for this question.

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Discontinuation by "tapering" vs usual family planning care

Relapse · participants with depressive or anxiety disorders

It is very uncertain whether discontinuation by "tapering" changes relapse (as defined by study authors) (HR) compared with continuation (or usual care) (very low certainty).

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
HR 2.97 [2.24, 3.93]
13 studies · 1546 participants
Very low

Discontinuation by "tapering" vs usual family planning care

Withdrawal symptoms · participants with depressive or anxiety disorders

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 176 participants
Very low

Discontinuation by "tapering" vs usual family planning care

Adverse events · participants with depressive or anxiety disorders

It is very uncertain whether discontinuation by "tapering" changes adverse events compared with continuation (or usual care) (very low certainty).

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
OR 1.06 [0.82, 1.38]
7 studies · 1479 participants
Very low

Discontinuation by "tapering" vs usual family planning care

Depressive symptoms · participants with depressive or anxiety disorders

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1017 participants
Very low

Discontinuation by "tapering" vs usual family planning care

Anxiety · participants with depressive or anxiety disorders

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 526 participants
Very low

Discontinuation by "tapering" vs usual family planning care

Quality of life · participants with depressive or anxiety disorders

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 502 participants
Very low

Discontinuation by "tapering" vs usual family planning care

Social and occupational functioning · participants with depressive or anxiety disorders

1 finding from 1 review

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety… 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 502 participants
Very low