Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 5 findings · 1 reviews · Oral Health

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 5 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs placebo

Adverse effects: intermittent facial skin rash · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (alpha lipoic acid +/- adjunctive ingredients) changes adverse effects: intermittent facial skin rash compared with placebo (very low certainty).

1 finding from 1 review

Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs placebo

Gastrointestinal adverse events · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (alpha lipoic acid +/- adjunctive ingredients) changes adverse effects: gastrointestinal complaints compared with placebo (very low certainty).

1 finding from 1 review

Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs placebo

Somnolence · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (alpha lipoic acid +/- adjunctive ingredients) changes adverse effects: drowsiness compared with placebo (very low certainty).

1 finding from 1 review

Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs placebo

Adverse effects: headache · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (alpha lipoic acid +/- adjunctive ingredients) changes adverse effects: headache compared with placebo (very low certainty).

1 finding from 1 review

Dietary supplements (alpha lipoic acid +/- adjunctive ingredients) vs placebo

Adverse events: worsening of hypertension · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (alpha lipoic acid +/- adjunctive ingredients) changes adverse effects: increase in blood pressure compared with placebo (very low certainty).

1 finding from 1 review