Dental caries (ECC/severe ECC) as exposure/grouping vs Caries-free controls
Relative abundance of S. mutans in saliva · Individuals assessed for dental caries, predominantly children with early childhood caries (ECC) or severe ECC (age about 1 to 4 years)
A few small studies report Streptococcus mutans relative abundance in caries versus caries-free children without pooling; the evidence is ungraded and not meta-analyzed.
1 finding from 1 review
- A systematic review of Streptococcus Mutans and Veillonellae species interactions in dental caries progression:… 2025 All outcomesCommunity and clinical pediatric dental settings (USA, Hong Kong, Indonesia); saliva or dental plaque microbial samplingReported in 2 studies without pooling: Agnello 2017 median S. mutans relative abundance 0.73% (0.02-22.9) in caries vs 0.15% (0.006-10.4) in controls; Chalmers 2015 Streptococcus 35.63+/-17.04 (caries) vs 32.11+/-18.91…1 study · 50 participantsGRADE not reported